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JUVENILE HUNTINGTON DISEASE
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DeCS
Descriptor
English
:
Huntington Disease
Descriptor
Spanish
:
Enfermedad de Huntington
Descriptor
Portuguese
:
Doença de Huntington
Synonyms
English
:
Huntington Chorea
Juvenile Huntington Disease
Tree Number:
C10.228.140.079.545
C10.228.140.380.278
C10.228.662.262.249.750
C10.574.500.497
C16.320.400.430
F03.087.250.400
F03.087.400.390
Definition
English
:
A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive
CHOREA
and
DEMENTIA
in the fourth or fifth decade of
life
. Common initial manifestations include paranoia; poor impulse
control
;
DEPRESSION
;
HALLUCINATIONS
; and
DELUSIONS
. Eventually intellectual impairment; loss of fine motor
control
;
ATHETOSIS
; and diffuse
chorea
involving axial and limb musculature develops, leading to a vegetative
state
within 10-15 years of
disease
onset. The juvenile variant has a more fulminant course including
SEIZURES
;
ATAXIA
;
dementia
; and
chorea
. (From Adams et al., Principles of
Neurology
, 6th ed, pp1060-4)
History Note
English
:
2000(1963)
Allowable Qualifiers
English
:
BL
blood
CF
cerebrospinal fluid
CI
chemically induced
CL
classification
CO
complications
DI
diagnosis
DH
diet therapy
DT
drug therapy
EC
economics
EM
embryology
EN
enzymology
EP
epidemiology
EH
ethnology
ET
etiology
GE
genetics
HI
history
IM
immunology
ME
metabolism
MI
microbiology
MO
mortality
NU
nursing
PS
parasitology
PA
pathology
PP
physiopathology
PC
prevention & control
PX
psychology
RA
radiography
RI
radionuclide imaging
RT
radiotherapy
RH
rehabilitation
SU
surgery
TH
therapy
US
ultrasonography
UR
urine
VE
veterinary
VI
virology
Record Number:
30920
Unique Identifier:
D006816
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS